Fine tuning the structure of the Cu2+ complex with the prion protein chicken repeat by proline isomerization

被引：15

作者：

Stanczak, P

Valensin, D

Juszczyk, P

Grzonka, Z

Valensin, G

Bernardi, F

Molteni, E

Gaggelli, E

Kozlowski, H

机构：

[1] Univ Wroclaw, Fac Chem, PL-50383 Wroclaw, Poland

[2] Univ Siena, Dept Chem, I-53100 Siena, Italy

[3] Univ Gdansk, Fac Chem, PL-80952 Gdansk, Poland

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 26期

关键词：

D O I：

10.1039/b504986e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The interaction between the single hexarepeat unit of chicken prion protein [ChPrP(54-59)] and Cu(II) was investigated by NMR, finding different coordination modes for the trans/trans and cis/trans isomers.

引用

页码：3298 / 3300

页数：3

共 34 条

[1]

Banci L., 1991, NUCL ELECT RELAXATIO

[2] SCRAPIE AND CELLULAR PRION PROTEINS DIFFER IN THEIR KINETICS OF SYNTHESIS AND TOPOLOGY IN CULTURED-CELLS [J].

BORCHELT, DR ;

SCOTT, M ;

TARABOULOS, A ;

STAHL, N ;

PRUSINER, SB .

JOURNAL OF CELL BIOLOGY, 1990, 110 (03) :743-752

[3]

BORCHELT DR, 1992, J BIOL CHEM, V267, P16188

[4] Topics in prion cell biology [J].

Brockes, JP .

CURRENT OPINION IN NEUROBIOLOGY, 1999, 9 (05) :571-577

[5] Prion and prejudice: normal protein and the synapse [J].

Brown, DR .

TRENDS IN NEUROSCIENCES, 2001, 24 (02) :85-90

[6] Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases [J].

Brown, DR ;

Kozlowski, H .

DALTON TRANSACTIONS, 2004, (13) :1907-1917

[7] Copper and zinc cause delivery of the prion protein from the plasma membrane to a subset of early endosomes and the Golgi [J].

Brown, LR ;

Harris, DA .

JOURNAL OF NEUROCHEMISTRY, 2003, 87 (02) :353-363

[8] Molecular features of the copper binding sites in the octarepeat domain of the prion protein [J].

Burns, CS ;

Aronoff-Spencer, E ;

Dunham, CM ;

Lario, P ;

Avdievich, NI ;

Antholine, WE ;

Olmstead, MM ;

Vrielink, A ;

Gerfen, GJ ;

Peisach, J ;

Scott, WG ;

Millhauser, GL .

BIOCHEMISTRY, 2002, 41 (12) :3991-4001

[9] Prion protein NMR structures of chickens, turtles, and frogs [J].

Calzolai, L ;

Lysek, DA ;

Pérez, DR ;

Güntert, P ;

Wüthrich, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (03) :651-655

[10] Prion diseases of humans and animals: Their causes and molecular basis [J].

Collinge, J .

ANNUAL REVIEW OF NEUROSCIENCE, 2001, 24 :519-550

← 1 2 3 4 →