Evaluation of four whole-cell Leptospira-based serological tests for diagnosis of urban leptospirosis

被引：32

作者：

McBride, Alan J. A.

Santos, Balbino L.

Queiroz, Adriano

Santos, Andreia C.

Hartskeerl, Rudy A.

Reis, Mitermayer G.

Ko, Albert I.

机构：

[1] Fundacao Oswaldo Cruz, Ctr Pesquisas Goncalo Moniz, Minist Hlth, BR-40295001 Salvador, BA, Brazil

[2] Royal Trop Inst KIT, Dept Biomed Res, NL-1105 AZ Amsterdam, Netherlands

[3] Cornell Univ, Weill Med Coll, Div Infect Dis & Internal Med, New York, NY USA

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2007年 / 14卷 / 09期

关键词：

D O I：

10.1128/CVI.00217-07

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Four serologic assays for leptospirosis had sensitivities of 72 to 88% and specificities of 88 to 100% in the setting of highly endemic urban transmission, indicating that assays using enzyme-linked immunosorbency and rapid formats may be used as alternatives to the microscopic agglutination test for diagnosing urban leptospirosis. Testing a second sample will be required in cases with an initial negative result, since sensitivity was low (46 to 68%) during the first week of illness.

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页码：1245 / 1248

页数：4

相关论文

共 39 条

[1] ANTIBODIES INVOLVED IN HUMAN IMMUNE-RESPONSE TO LEPTOSPIRAL INFECTION [J].

ADLER, B ;

FAINE, S .

JOURNAL OF MEDICAL MICROBIOLOGY, 1978, 11 (04) :387-400

[2] Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis [J].

Bajani, MD ;

Ashford, DA ;

Bragg, SL ;

Woods, CW ;

Aye, T ;

Spiegel, RA ;

Plikaytis, BD ;

Perkins, BA ;

Phelan, M ;

Levett, PN ;

Weyant, RS .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (02) :803-809

[3]

Bharadwaj R, 2002, JPN J INFECT DIS, V55, P194

[4] Leptospirosis: a zoonotic disease of global importance [J].

Bharti, AR ;

Nally, JE ;

Ricaldi, JN ;

Matthias, MA ;

Diaz, MM ;

Lovett, MA ;

Levett, PN ;

Gilman, RH ;

Willig, MR ;

Gotuzzo, E ;

Vinetz, JM .

LANCET INFECTIOUS DISEASES, 2003, 3 (12) :757-771

[5] Limited diagnostic capacities of two commercial assays for the detection of Leptospira immunoglobulin m antibodies in Laos [J].

Blacksell, Stuart D. ;

Smythe, Lee ;

Phetsouvanh, Rattanaphone ;

Dohnt, Michael ;

Hartskeerl, Rudy ;

SymondS, Meegan ;

Slack, Andrew ;

Vongsouvath, Manivanh ;

Davong, Viengmone ;

Lattana, Olay ;

Phongmany, Simmaly ;

Keolouangkot, Valy ;

White, Nicholas J. ;

Day, Nicholas P. J. ;

Newton, Paul N. .

CLINICAL AND VACCINE IMMUNOLOGY, 2006, 13 (10) :1166-1169

[6] Leptospira immunoglobulin-like proteins as a serodiagnostic marker for acute leptospirosis [J].

Croda, Julio ;

Ramos, Joao G. R. ;

Matsunaga, James ;

Queiroz, Adriano ;

Homma, Akira ;

Riley, Lee W. ;

Haake, David A. ;

Reis, Mitermayer G. ;

Ko, Albert I. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (05) :1528-1534

[7] Evaluation of the indirect hemagglutination assay for diagnosis of acute leptospirosis in Hawaii [J].

Effler, PV ;

Domen, HY ;

Bragg, SL ;

Aye, T ;

Sasaki, DM .

JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (03) :1081-1084

[8] Evaluation of eight rapid screening tests for acute leptospirosis in Hawaii [J].

Effler, PV ;

Bogard, AK ;

Domen, HY ;

Katz, AR ;

Higa, HY ;

Sasaki, DM .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (04) :1464-1469

[9]

Faine S., 1999, LEPTOSPIRA LEPTOSPIR

[10] LEPTOSPIROSIS [J].

FARR, RW .

CLINICAL INFECTIOUS DISEASES, 1995, 21 (01) :1-6

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