Detection of hepatitis E virus in archived German wild boar serum samples

被引：74

作者：

Kaci, Sadia ^{[1
]}

Noeckler, Karsten ^{[1
]}

Johne, Reimar ^{[1
]}

机构：

[1] Fed Inst Risk Assessment, D-12277 Berlin, Germany

来源：

VETERINARY MICROBIOLOGY | 2008年 / 128卷 / 3-4期

关键词：

hepatitis E virus; wild boar; zoonotic transmission; phylogenetic analysis; archived samples;

D O I：

10.1016/j.vetmic.2007.10.030

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Hepatitis E is a rare human disease in Central Europe commonly imported from endemic regions. For autochthonous infections a zoonotic transmission from pigs, deer and wild boar is assumed. Using three different RT-PCR protocols, hepatitis E virus (HEV) RNA was detected in 10 out of 189 (5.3%) serum samples collected in 1995/1996 from wild boars in Germany. Sequence analysis indicates a close relationship with genotype 3 isolates of pigs and humans from the Netherlands and Japan. The results indicate that HEV is present in Germany since more than 10 years and that wild boar may function as a reservoir for HEV. (C) 2007 Elsevier B.V. All rights reserved.

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页码：380 / 385

页数：6

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