Fabrication, modification, and application of department of analytical poly(methyl methacrylate) microfluidic chips

被引:125
作者
Chen, Yun [1 ]
Zhang, Luyan [1 ]
Chen, Gang [1 ]
机构
[1] Fudan Univ, Sch Pharm, Dept Analyt Chem, Shanghai 200032, Peoples R China
关键词
capillary electrophoresis; microfluiclic chips; modification; poly(methyl methacrylate);
D O I
10.1002/elps.200700552
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Poly(methyl methacrylate) (PMMA) is particularly useful for microfluidic chips with the features of low price, excellent optic transparency, attractive mechanical and chemical properties, ease of fabrication and modification, biocompatibility, etc. During the past decade, significant progress in the PMMA microfluidic chips has occurred. This review, which contains 120 references, summarizes the recent advances and the key strategies in the fabrication, modification, and application of PMMA microfluidic chips. It is expected that PMMA microchips should find a wide range of applications and will lead to the creation of truly disposable microfluidic devices.
引用
收藏
页码:1801 / 1814
页数:14
相关论文
共 132 条
[1]   Determination of biochemical species on electrophoresis chips with an external contactless conductivity detector [J].
Abad-Villar, EM ;
Kubán, P ;
Hauser, PC .
ELECTROPHORESIS, 2005, 26 (19) :3609-3614
[2]   Detection of human immunoglobulin in microchip and conventional capillary electrophoresis with contactless conductivity measurements [J].
Abad-Villar, EM ;
Tanyanyiwa, J ;
Fernández-Abedul, MT ;
Costa-García, A ;
Hauser, PC .
ANALYTICAL CHEMISTRY, 2004, 76 (05) :1282-1288
[3]   Micro total analysis systems. 2. Analytical standard operations and applications [J].
Auroux, PA ;
Iossifidis, D ;
Reyes, DR ;
Manz, A .
ANALYTICAL CHEMISTRY, 2002, 74 (12) :2637-2652
[4]   Surface modification for enhancing antibody binding on polymer-based microfluidic device for enzyme-linked immunosorbent assay [J].
Bai, Yunling ;
Koh, Chee Guan ;
Boreman, Megan ;
Juang, Yi-Je ;
Tang, I-Ching ;
Lee, L. James ;
Yang, Shang-Tian .
LANGMUIR, 2006, 22 (22) :9458-9467
[5]   Plastic microfluidic devices modified with polyelectrolyte multilayers [J].
Barker, SLR ;
Tarlov, MJ ;
Canavan, H ;
Hickman, JJ ;
Locascio, LE .
ANALYTICAL CHEMISTRY, 2000, 72 (20) :4899-4903
[6]  
Becker H, 2000, ELECTROPHORESIS, V21, P12, DOI 10.1002/(SICI)1522-2683(20000101)21:1<12::AID-ELPS12>3.0.CO
[7]  
2-7
[8]   Polymer microfluidic devices [J].
Becker, H ;
Locascio, LE .
TALANTA, 2002, 56 (02) :267-287
[9]   Deposition of PEG onto PMMA microchannel surface to minimize nonspecific adsorption [J].
Bi, Hongyan ;
Meng, Sheng ;
Li, Yan ;
Guo, Kai ;
Chen, Yupeng ;
Kong, Jilie ;
Yang, Pengyuan ;
Zhong, Wei ;
Liu, Baohong .
LAB ON A CHIP, 2006, 6 (06) :769-775
[10]   Strategy for allosteric analysis based on protein-patterned stationary phase in microfluidic chip [J].
Bi, HY ;
Weng, XX ;
Qu, HY ;
Kong, JL ;
Yang, PY ;
Liu, BH .
JOURNAL OF PROTEOME RESEARCH, 2005, 4 (06) :2154-2160