Coagulation and fibrinolysis parameters in normal pregnancy and in gestational diabetes

被引：38

作者：

Bellart, J ^{[1
]}

Gilabert, R ^{[1
]}

Fontcuberta, F ^{[1
]}

Carreras, E ^{[1
]}

Miralles, RM ^{[1
]}

Cabero, L ^{[1
]}

机构：

[1] Hosp Univ Tarragona Joan XXIII, Serv Obstet & Ginecol, Unitat Med Materno Fetal, Tarragona 43007, Spain

来源：

AMERICAN JOURNAL OF PERINATOLOGY | 1998年 / 15卷 / 08期

关键词：

coagulation; fibrinolysis; pregnancy; diabetes;

D O I：

10.1055/s-2007-994069

中图分类号：

R71 [妇产科学];

学科分类号：

100211 [妇产科学];

摘要：

The changes in coagulation and fibrinolysis parameters during pregnancy, delivery and 3 days after delivery were evaluated in normotensive and gestational diabetes pregnant women. Normal pregnant women (n = 60) and pregnant women with gestational diabetes (n = 15) formed the study population. Coagulation and fibrinolysis parameters were estimated using commercial tests. Antithrombin III, thrombin-antithrombin III complexes, heparin cofactor II, protein C, protein S, tissue plasminogen activator, (t-PA) D-dimer and plasminogen activator inhibitor(PAI-1 and PAI-2) activities in normal and gestational diabetes pregnancies were determined. Thrombin-antithrombin III complexes increased and coagulation inhibitors decreased in gestational diabetes. Plasminogen activator inhibitors remained unchanged and t-PA levels increased in gestational diabetes.

引用

页码：479 / 486

页数：8

共 32 条

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AN ANTICOAGULANT DERMATAN SULFATE PROTEOGLYCAN CIRCULATES IN THE PREGNANT WOMAN AND HER FETUS [J].