Bifunctional cyclodextrin metalloenzyme mimics

被引：30

作者：

Dong, SD ^{[1
]}

Breslow, R ^{[1
]}

机构：

[1] Columbia Univ, Dept Chem, New York, NY 10027 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 51期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

tren; zinc; phosphate hydrolysis;

D O I：

10.1016/S0040-4039(98)02160-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of regioisomeric bifunctionalized beta-cyclodextrins derivatized with an imidazole and a metal ligand tris(2-aminoethyl)amine (tren) group were prepared. As their Zn2+ complexes, these compounds show bifunctional catalysis of phosphate hydrolysis with a regioisomeric preference. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：9343 / 9346

页数：4

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