Structurally simple lipid bilayer transport agents for chloride and bicarbonate

被引：89

作者：

Andrews, Natalie J. ^{[1
]}

Haynes, Cally J. E. ^{[1
]}

Light, Mark E. ^{[1
]}

Moore, Stephen J. ^{[1
]}

Tong, Christine C. ^{[1
]}

Davis, Jeffery T. ^{[2
]}

Harrell, William A., Jr. ^{[2
]}

Gale, Philip A. ^{[1
]}

机构：

[1] Univ Southampton, Sch Chem, Southampton, Hants, England

[2] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

来源：

CHEMICAL SCIENCE | 2011年 / 2卷 / 02期

基金：

英国工程与自然科学研究理事会;

关键词：

INDOLE-BASED MACROCYCLES; CONFORMATIONAL CONTROL; CARBOXYLATE COMPLEXATION; MEMBRANE TRANSPORTERS; ANION COMPLEXATION; CELL-MEMBRANES; FLIP-FLOP; RECEPTORS; VESICLE; 1,3-DIINDOLYLUREAS;

D O I：

10.1039/c0sc00503g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new series of structurally simple compounds containing thiourea groups have been shown by a combination of ion-selective electrode and C-13 NMR techniques to be potent chloride-bicarbonate exchange agents that function at low concentration in POPC and POPC/cholesterol membranes.

引用

页码：256 / 260

页数：5

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