Recent progress in the pharmacology of imidazo[1,2-a]pyridines

被引:520
作者
Enguehard-Gueiffier, Cecile [1 ]
Gueiffier, Alain [1 ]
机构
[1] SPOT EA 3857, Fac Pharm, Med Chem Lab, F-37200 Tours, France
关键词
imidazo[1,2-a]pyridine; pharmacological properties; enzyme inhibitors; receptor ligands; anti-infectious agents;
D O I
10.2174/138955707781662645
中图分类号
R914 [药物化学];
学科分类号
100701 [药物化学];
摘要
Imidazo[1,2-a]pyridine is a bicyclic system with a bridgehead nitrogen atom, of growing interest in medicinal chemistry. The paper deals with the recent progress realised in the comprehension of the pharmacological properties of this scaffold. From the many imidazo[1,2-a]pyridine analogues described in the literature, those discussed herein will be presented in three parts concerning first the enzyme inhibitors, then the receptor ligands and finally the anti-infectious agents.
引用
收藏
页码:888 / 899
页数:12
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