Novel PdII-mediated cascade carboxylative annulation to construct benzo[b]furan-3-carboxylic acids

被引：66

作者：

Liao, Y

Smith, J

Fathi, R

Yang, Z

机构：

[1] VivoQuest Inc, New York, NY 10989 USA

[2] Peking Univ, Coll Chem, Dept Biol Chem, Minist Educ,Key Lab Bioorgan Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 13期

关键词：

D O I：

10.1021/ol050876g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzo[b]furan-3-carboxylic acid (2) was generated from 1 by forming three new bonds in one step via a Pd-II-mediated cascade carboxylative annulation. The proposed mechanism was supported by the observation of an unusual acetylation of 1 as a side reaction together with an O-18-labeling study.

引用

页码：2707 / 2709

页数：3

共 17 条

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