Streptocidins A∼D, novel cyclic decapeptide antibiotics produced by Streptomyces sp Tu 6071 I.: Taxonomy, fermentation, isoltation anal biological activities

被引：16

作者：

Gebhardt, K

Pukall, R

Fiedler, HP

机构：

[1] Univ Tubingen, Inst Mikrobiol, D-72076 Tubingen, Germany

[2] DSMZ German Collect Microorganisms & Cell Culture, D-38124 Braunschweig, Germany

来源：

JOURNAL OF ANTIBIOTICS | 2001年 / 54卷 / 05期

关键词：

D O I：

10.7164/antibiotics.54.428

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Four never cyclic homodecapetide antibiotics, streptocidins A similar toD were detected in the mycelium extract of Streptomyces sp. Tu 6071 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. The peptides which were closely related in structure to the tyrocidines and gramicidins of Bacillus brevis show antibiotic activities against Gram-positive bacteria.

引用

页码：428 / 433

页数：6

共 18 条

[1] DNA AMPLIFICATION AND AN UNSTABLE ARGININE GENE IN STREPTOMYCES-LIVIDANS 66 [J].