Efficient hydrolysis of β-aminosulfamic acids using a Lewis acid and a thiol for the synthesis of 2,3-diaminopropanoate derivatives

被引：30

作者：

Kim, BM ^{[1
]}

So, SM

机构：

[1] Seoul Natl Univ, Dept Chem, Seoul 151742, South Korea

[2] Seoul Natl Univ, Ctr Mol Catalysis, Seoul 151742, South Korea

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 30期

关键词：

amino acids and derivatives; sulfamic acid and derivatives; hydrolysis;

D O I：

10.1016/S0040-4039(98)01079-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New hydrolysis conditions for beta-aminosulfamic acids produced from the opening of a cyclic sulfamidate with a variety of primary or secondary amines have been developed. This new hydrolysis method allowed us to use at most two equivalents of amine nucleophiles furnishing 2,3-diaminopropanoate derivatives in good to excellent yields. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5381 / 5384

页数：4

共 26 条

[1] Use of cyclic sulfamidates derived from D-allosamine in nucleophilic displacements: Scope and limitations [J].