Fluorinated Johnson reagent for transfer-trifluoromethylation to carbon nucleophiles

被引：166

作者：

Noritake, Shun ^{[1
]}

Shibata, Norio ^{[1
]}

Nakamura, Shuichi ^{[1
]}

Toru, Takeshi ^{[1
]}

Shiro, Motoo ^{[2
]}

机构：

[1] Nagoya Inst Technol, Dept Frontier Mat, Grad Sch Engn, Showa Ku, Nagoya, Aichi 4668555, Japan

[2] Rigaku Corp, Tokyo 1968666, Japan

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 2008卷 / 20期

关键词：

fluorine; trifluoromethylation; electrophilic; sulfur; C-C bond formation;

D O I：

10.1002/ejoc.200800419

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel reagent, [(oxido)phenyl(trifluoromethyl)-lambda(4)-sulfanylidene]dimethylammonium tetrafluoroborate has been developed for the electrophilic trifluoromethylation of carbon nucleophiles. The reagent was designed as a trifluorinated version of a Johnson-type methyl-transfer reagent. The first example of vinylogous trifluoromethylation of dicyanoalkylidenes is also demonstrated. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).

引用

页码：3465 / 3468

页数：4

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