Visual object agnosia and pure word alexia - Correlation of functional magnetic resonance imaging and lesion localization

被引：14

作者：

Salvan, CV

Ulmer, JL

DeYoe, EA

Wascher, T

Mathews, VP

Lewis, JW

Prost, RW

机构：

[1] Med Coll Wisconsin, Dept Radiol, Div Neuroradiol, Milwaukee, WI 53226 USA

[2] Neurospine Ctr Wisconsin, Green Bay, WI USA

[3] Indiana Univ, Med Ctr, Dept Radiol, Indianapolis, IN USA

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 2004年 / 28卷 / 01期

关键词：

bold oxygen level dependent (BOLD); functional magnetic resonance imaging (fMRI); object recognition; ventral occipito-temporal cortex (VOTC); word recognition;

D O I：

10.1097/00004728-200401000-00010

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We present a case of a 64-year-old, right-handed female with a metastatic breast cancer lesion involving the left posterior inferior temporal lobe causing complete loss of the ability to recognize visually common objects and words. After her symptoms resolved on corticosteroid therapy, functional magnetic resonance imaging (fMRI) mapping demonstrated strong left-hemispheric dominance for word recognition and right-hemispheric dominance for object recognition. The case illustrates the relationships among ventral occipito-temporal cortical activation, lesion localization, and lesioninduced deficits of higher visual function. The relationship between hemispheric dominance determined by fMRI and risk of postoperative deficit depends on the specific visual function of interest.

引用

页码：63 / 67

页数：5