Novel nirK cluster genes in Nitrosomonas europaea are required for NirK-dependent tolerance to nitrite

被引:47
作者
Beaumont, HJE [1 ]
Lens, SI [1 ]
Westerhoff, HV [1 ]
van Spanning, RJA [1 ]
机构
[1] Vrije Univ Amsterdam, Bioctr Amsterdam, Dept Mol Cell Physiol, NL-1081 HV Amsterdam, Netherlands
关键词
D O I
10.1128/JB.187.19.6849-6851.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Nitrite reductase (NirK) of Nitrosomonas europaea confers tolerance to nitrite (NO2-). The nirK gene is clustered with three genes of unknown physiological function: ncgABC. At present, this organization is unique to nitrifying bacteria. Here we report that the ncgABC gene products facilitate NirK-dependent NO2- tolerance by reversing the negative physiological effect that is associated with the activity of NirK in their absence. We hypothesize that the ncg gene products are involved in the detoxification of nitric oxide that is produced by NirK.
引用
收藏
页码:6849 / 6851
页数:3
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