Pentobarbital-induced modulation of flexor and H-reflexes in Spinal rats

被引：6

作者：

Duke, M ^{[1
]}

Advokat, C ^{[1
]}

机构：

[1] Louisiana State Univ, Dept Psychol, Baton Rouge, LA 70803 USA

来源：

BRAIN RESEARCH | 2000年 / 881卷 / 02期

关键词：

spasticity; Spinal rat; flexor reflex; H-reflex; rate dependent suppression; baclofen;

D O I：

10.1016/S0006-8993(00)02810-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Electrophysiological recordings of the H-reflex and nonnociceptive flexion reflex were obtained from pentobarbital-anesthetized Intact rats and from both, anesthetized and unanesthetized groups of Acute and Chronic Spinal rats. Results showed that the flexor, but not H-reflex, of Chronic Spinal rats was significantly larger than that of all other groups, which did not differ among themselves. The antispastic drug baclofen dose-dependently decreased the flexion response of Chronic Spinal rats (A(50)=4.3 mg/kg+/-2.1 and 9.0 mg/kg). (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：217 / 221

页数：5

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