Well-defined linear multiblock and branched polypeptides by linking chemistry

被引：33

作者：

Aliferis, T ^{[1
]}

Iatrou, H ^{[1
]}

Hadjichristidis, N ^{[1
]}

机构：

[1] Univ Athens, Dept Chem, GR-15771 Athens, Greece

来源：

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 2005年 / 43卷 / 19期

关键词：

block copolypeptides; light scattering; living polymerization; ring-opening polymerization; star copolypeptides;

D O I：

10.1002/pola.20926

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The synthesis of linear multiblock copolypeptides along with three-arm star homo- and copolypeptides was investigated. The precursors along with the final copolypeptides were characterized by membrane osmometry and size exclusion chromatography (SEC) featuring a two-angle laser scattering (TALLS) detector. In both methods, the measurements were performed at 60°C and the solvent was a 0.1N LiBr solution in N,N'-dimethylformamide (DMF). It was concluded that the livingness of the polypeptides under high-vacuum (HV) conditions can be preserved indefinitely and this allows the use of coupling chemistry for the synthesis of homo- and copolypeptides with a wide variety of macromolecular architectures.

引用

页码：4670 / 4673

页数：4

共 18 条

[1] Living polypeptides [J].