Determination of catecholamines in human plasma by HPLC with electrochemical detection

被引：19

作者：

Javidan, S ^{[1
]}

Cwik, MJ ^{[1
]}

机构：

[1] UNIV ILLINOIS, COLL PHARM, CLIN RES LAB, CHICAGO, IL 60612 USA

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 1996年 / 19卷 / 08期

关键词：

D O I：

10.1080/10826079608006322

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An assay procedure is described to quantitate low picogram concentrations of catecholamines in human plasma using reversed phase ion-pair HPLC with electrochemical detection. Optimization of chromatographic conditions allows use of samples as small as 0.25 mL. The overall recovery of 78% offers high precision and accuracy at low concentrations. The lower limit of detection is 0.87 pg/mL for epinephrine, 3.5 pg/mL for norepinephrine and 8.3 pg/mL for dopamine.

引用

页码：1339 / 1348

页数：10

共 27 条

[1] ANTON AH, 1962, J PHARMACOL EXP THER, V138, P360
[2] A GENERAL-METHOD FOR THE QUANTITATIVE-DETERMINATION OF CATECHOLAMINES IN BODY-FLUIDS USING OFF-LINE SAMPLE PRETREATMENT AND HPLC-ED ANALYSIS
BAUCH, HJ
STRUWER, E
KELSCH, U
[J]. CHROMATOGRAPHIA, 1989, 28 (1-2) : 78 - 84
[3] BUHLER HU, 1978, J PHYSIOL-LONDON, V276, P311, DOI 10.1113/jphysiol.1978.sp012235
[4] PLASMA-CATECHOLAMINE LEVELS IN CHILDREN
CANDITO, M
ALBERTINI, M
POLITANO, S
DEVILLE, A
MARIANI, R
CHAMBON, P
[J]. JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1993, 617 (02): : 304 - 307
[5] ANALYSIS OF RAT-BRAIN MICRODIALYSATE BY GAS-CHROMATOGRAPHY HIGH-RESOLUTION SELECTED-ION MONITORING MASS-SPECTROMETRY
CHANG, SY
MOORE, TA
DEVAUD, LL
TAYLOR, LCE
HOLLINGSWORTH, EB
[J]. JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1991, 562 (1-2): : 111 - 118
[6] SIMULTANEOUS MEASUREMENT OF PLASMA SEROTONIN, CATECHOLAMINES, AND THEIR METABOLITES BY AN IN-VITRO MICRODIALYSIS-MICROBORE HPLC AND A DUAL AMPEROMETRIC DETECTOR
CHENG, FC
LIN, NN
KUO, JS
CHENG, LJ
CHANG, FM
CHIA, LG
[J]. ELECTROANALYSIS, 1994, 6 (10) : 871 - 877
[7] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS WITH ELECTROCHEMICAL DETECTION OF BIOGENIC-AMINES USING MICROBORE COLUMNS
CHENG, FC
KUO, JS
[J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1995, 665 (01): : 1 - 13
[8] DETERMINATION OF CATECHOLAMINES IN URINE (AND PLASMA) BY LIQUID-CHROMATOGRAPHY AFTER ONLINE SAMPLE PRETREATMENT ON SMALL ALUMINA OR DIHYDROXYBORYLSILICA COLUMNS
DEJONG, J
POINT, AJF
TJADEN, UR
BEEKSMA, S
KRAAK, JC
[J]. JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1987, 414 (02): : 285 - 300
[9] THE CARDIOVASCULAR EFFECTS OF DOPAMINE IN THE SEVERELY ASPHYXIATED NEONATE
DISESSA, TG
LEITNER, M
TI, CC
GLUCK, L
COEN, R
FRIEDMAN, WF
[J]. JOURNAL OF PEDIATRICS, 1981, 99 (05) : 772 - 776
[10] DETERMINATION OF CATECHOLAMINES IN RAT-HEART TISSUE AND PLASMA SAMPLES BY LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION
ERIKSSON, BM
PERSSON, BA
[J]. JOURNAL OF CHROMATOGRAPHY, 1982, 228 (MAR): : 143 - 154

← 1 2 3 →