The Role of Biventricular Pacing in the Prevention and Therapy of Pacemaker-Induced Cardiomyopathy

被引：12

作者：

Guglin, Maya ^{[1
]}

Barold, S. Serge ^{[2
]}

机构：

[1] Univ Kentucky, Lexington, KY 40507 USA

[2] Univ Rochester, Sch Med & Dent, Rochester, NY USA

来源：

ANNALS OF NONINVASIVE ELECTROCARDIOLOGY | 2015年 / 20卷 / 03期

关键词：

pacemaker-mediated cardiomyopathy; cardiac resynchronization therapy; heart failure; CARDIAC RESYNCHRONIZATION THERAPY; ATRIOVENTRICULAR JUNCTION ABLATION; CONGESTIVE-HEART-FAILURE; RIGHT-VENTRICULAR STIMULATION; SICK SINUS SYNDROME; PACED QRS DURATION; ATRIAL-FIBRILLATION; DEPENDENT PATIENTS; DUAL-CHAMBER; CONVENTIONAL PACEMAKERS;

D O I：

10.1111/anec.12245

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Right ventricular (RV) pacing produces well-known long-term deleterious effects not only on already compromised, but also on the normal left ventricle (LV). The activation pattern mimicks that of left bundle branch block, with delayed activation of the LV free wall, and results in electrical and mechanical dyssynchrony. Long-term mandatory (100%) RV pacing, increases LV dimensions and decreases the ejection fraction. Many of these negative effects of pacing can be overcome by biventricular pacing. In this review, we describe the characteristics of pacemaker-induced cardiomyopathy, its incidence, and the use of cardiac resynchronization therapy (CRT) for its therapy and prevention. The gaps in the current organizational guidelines for using CRT in the treatment of bradycardia are identified, and goals for future research are discussed.

引用

页码：224 / 239

页数：16

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