What we know so far: COVID-19 current clinical knowledge and research

被引:475
作者
Lake, Mary A. [1 ]
机构
[1] Univ Cambridge, Cambridge, England
关键词
2019-nCoV; coronavirus; Wuhan; respiratory tract infection; SARS-CoV-2; SARS CORONAVIRUS;
D O I
10.7861/clinmed.2019-coron
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In December 2019, health authorities in Wuhan, China, identified a cluster of pneumonia cases of unknown aetiology linked to the city's South China Seafood Market. Subsequent investigations revealed a novel coronavirus, SARS-CoV-2, as the causative agent now at the heart of a major outbreak. The rising case numbers have been accompanied by unprecedented public health action, including the wholesale isolation of Wuhan. Alongside this has been a robust scientific response, including early publication of the pathogen genome, and rapid development of highly specific diagnostics. This article will review the new knowledge of SARS-CoV-2 COVID-19 acute respiratory disease, and summarise its clinical features.
引用
收藏
页码:124 / 127
页数:4
相关论文
共 29 条
[1]  
[Anonymous], 2020, SEV 2019 NCOVREMDESI
[2]   Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature [J].
Biggerstaff, Matthew ;
Cauchemez, Simon ;
Reed, Carrie ;
Gambhir, Manoj ;
Finelli, Lyn .
BMC INFECTIOUS DISEASES, 2014, 14
[3]   Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units [J].
Booth, TF ;
Kournikakis, B ;
Bastien, N ;
Ho, J ;
Kobasa, D ;
Stadnyk, L ;
Li, Y ;
Spence, M ;
Paton, S ;
Henry, B ;
Mederski, B ;
White, D ;
Low, DE ;
McGeer, A ;
Simor, A ;
Vearncombe, M ;
Downey, J ;
Jamieson, FB ;
Tang, P ;
Plummer, F .
JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (09) :1472-1477
[4]  
Callaway Ewen, 2020, Nature, DOI 10.1038/d41586-020-00180-8
[5]   A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster [J].
Chan, Jasper Fuk-Woo ;
Yuan, Shuofeng ;
Kok, Kin-Hang ;
To, Kelvin Kai-Wang ;
Chu, Hin ;
Yang, Jin ;
Xing, Fanfan ;
Liu, Jieling ;
Yip, Cyril Chik-Yan ;
Poon, Rosana Wing-Shan ;
Tsoi, Hoi-Wah ;
Lo, Simon Kam-Fai ;
Chan, Kwok-Hung ;
Poon, Vincent Kwok-Man ;
Chan, Wan-Mui ;
Ip, Jonathan Daniel ;
Cai, Jian-Piao ;
Cheng, Vincent Chi-Chung ;
Chen, Honglin ;
Hui, Christopher Kim-Ming ;
Yuen, Kwok-Yung .
LANCET, 2020, 395 (10223) :514-523
[6]  
Department of Health and Social Care Public Health England, 2020, COR LAT INF ADV
[7]   Severe acute respiratory syndrome coronavirus on hospital surfaces [J].
Dowell, SF ;
Simmerman, JM ;
Erdman, DD ;
Wu, JSJ ;
Chaovavanich, A ;
Javadi, M ;
Yang, JY ;
Anderson, LJ ;
Tong, SX ;
Ho, MS .
CLINICAL INFECTIOUS DISEASES, 2004, 39 (05) :652-657
[8]   Clinical Characteristics of Coronavirus Disease 2019 in China [J].
Guan, W. ;
Ni, Z. ;
Hu, Yu ;
Liang, W. ;
Ou, C. ;
He, J. ;
Liu, L. ;
Shan, H. ;
Lei, C. ;
Hui, D. S. C. ;
Du, B. ;
Li, L. ;
Zeng, G. ;
Yuen, K. -Y. ;
Chen, R. ;
Tang, C. ;
Wang, T. ;
Chen, P. ;
Xiang, J. ;
Li, S. ;
Wang, Jin-lin ;
Liang, Z. ;
Peng, Y. ;
Wei, L. ;
Liu, Y. ;
Hu, Ya-hua ;
Peng, P. ;
Wang, Jian-ming ;
Liu, J. ;
Chen, Z. ;
Li, G. ;
Zheng, Z. ;
Qiu, S. ;
Luo, J. ;
Ye, C. ;
Zhu, S. ;
Zhong, N. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (18) :1708-1720
[9]   Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China [J].
Guan, Y ;
Zheng, BJ ;
He, YQ ;
Liu, XL ;
Zhuang, ZX ;
Cheung, CL ;
Luo, SW ;
Li, PH ;
Zhang, LJ ;
Guan, YJ ;
Butt, KM ;
Wong, KL ;
Chan, KW ;
Lim, W ;
Shortridge, KF ;
Yuen, KY ;
Peiris, JSM ;
Poon, LLM .
SCIENCE, 2003, 302 (5643) :276-278
[10]   The basic reproduction number (R0) of measles: a systematic review [J].
Guerra, Fiona M. ;
Bolotin, Shelly ;
Lim, Gillian ;
Heffernan, Jane ;
Deeks, Shelley L. ;
Li, Ye ;
Crowcroft, Natasha S. .
LANCET INFECTIOUS DISEASES, 2017, 17 (12) :E420-E428