Antiviral activity of galangin isolated from the aerial parts of Helichrysum aureonitens

被引：108

作者：

Meyer, JJM ^{[1
]}

Afolayan, AJ ^{[1
]}

Taylor, MB ^{[1
]}

Erasmus, D ^{[1
]}

机构：

[1] UNIV PRETORIA,DEPT MED VIROL,INST PATHOL,ZA-0001 PRETORIA,SOUTH AFRICA

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1997年 / 56卷 / 02期

关键词：

3,5,7-trihydroxyflavone; antiviral; galangin; Helichrysum aureonitens; medicinal;

D O I：

10.1016/S0378-8741(97)01514-6

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The in vitro antiviral activity of galangin (3,5,7-trihydroxyflavone), the major antimicrobial compound isolated from the shoots of Helichrysum aureonitens, was investigated against herpes simplex virus type 1 (HSV-1), coxsackie B virus type 1 (Cox B1), adenovirus type 31 (Ad31) and reovirus. At concentrations ranging from 12-47 mu g/ml galangin showed significant antiviral activity against HSV-1 and CoxB1, limited activity against reovirus, and no antiviral activity against Ad31. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：165 / 169

页数：5

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