A two-photon fluorescent probe for calcium waves in living tissue

被引：97

作者：

Kim, Hwan Myung ^{[1
]}

Kim, Bo Ra ^{[1
]}

Hong, Jin Hee ^{[1
]}

Park, Jin-Sung ^{[1
]}

Lee, Kyoung J. ^{[1
]}

Cho, Bong Rae ^{[1
]}

机构：

[1] Korea Univ, Ctr Electro & Photorespons Mol, Dept Chem, Seoul 136701, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 39期

关键词：

calcium; fluorescence; microscopy; two-photon probes;

D O I：

10.1002/anie.200701720

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Intracellular messaging: The novel two-photon fluorescent probe ACa1 can visualize calcium waves in cells and living tissue for a long period of time and without any mistargeting problems (see picture). The probe is capable of monitoring the calcium waves at a depth of about 150 μm in living tissues for more than 1100 s and with no photobleaching artifacts. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7445 / 7448

页数：4

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