Ligand-gated calcium channels inside and out

被引：36

作者：

Striggow, F ^{[1
]}

Ehrlich, BE ^{[1
]}

机构：

[1] UNIV CONNECTICUT,DEPT PHYSIOL,LAB MOL HERMENEUT,FARMINGTON,CT 06030

来源：

CURRENT OPINION IN CELL BIOLOGY | 1996年 / 8卷 / 04期

关键词：

D O I：

10.1016/S0955-0674(96)80025-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Calcium release from intracellular stores occurs through two types of channels associated with intracellular membranes, namely, the ryanodine receptor and the inositol 1,4,5-trisphosphate receptor. Recently, it has been shown that these channels are regulated by allosteric mechanisms and associated proteins. Release of intracellular calcium induces the opening of calcium-permeable channels on the plasma membrane. Current work has focused on the molecular and functional characterization of these channels which have been identified as store-operated channels or calcium release activated channels.

引用

页码：490 / 495

页数：6

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