Optimal experimental design in chromatography

被引:33
作者
Atkinson, Anthony C. [1 ]
Tobias, Randall D. [2 ]
机构
[1] Univ London London Sch Econ & Polit Sci, Dept Stat, London WC2A 2AE, England
[2] SAS Inst, Cary, NC 27513 USA
关键词
D-optimal designs; equivalence theorem; response-surface design; small design;
D O I
10.1016/j.chroma.2007.11.045
中图分类号
Q5 [生物化学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
Many experimental programs in chromatography involve the estimation of a second-order response surface. The paper focuses on the use of the methods of optimal experimental design to find efficient response surface designs. We give tables of the properties of designs with two, three and four factors. References are given to tables of designs and to SAS programs for their construction. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 11
页数:11
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