Ca2+ signalling and Ca2+-activated ion channels in exocrine acinar cells

被引：88

作者：

Petersen, OH ^{[1
]}

机构：

[1] Univ Liverpool, Physiol Lab, MRC Grp, Liverpool L69 3BX, Merseyside, England

来源：

CELL CALCIUM | 2005年 / 38卷 / 3-4期

基金：

英国医学研究理事会;

关键词：

calcium-activated ion channels; calcium oscillations; IP3; receptors; ryanodine receptors; NAADP; cADPR;

D O I：

10.1016/j.ceca.2005.06.024

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The development of the calcium signalling field, from its early beginnings some 40 years ago to the present, is described. Calcium signalling in exocrine gland acinar cells and the effects of neurotransmitter- or horitione-elicited rises in the cytosolic calcium ion concentration on ion channel gating are reviewed. The highly polarized arrangement of the organelle systems in living acinar cells is described as well as its importance for the physiologically relevant local and polarized calcium signalling events. (C) 2005 Elsevier B.V. All rights reserved.

引用

页码：171 / 200

页数：30

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