HIV integrase, a brief overview from chemistry to therapeutics

[1] Molecular mechanisms in retrovirus DNA integration [J]. ANTIVIRAL RESEARCH, 1997, 36 (03) : 139 - 156

[2] STRUCTURAL BASIS FOR THE 3'-5' EXONUCLEASE ACTIVITY OF ESCHERICHIA-COLI DNA-POLYMERASE-I - A 2 METAL-ION MECHANISM [J]. EMBO JOURNAL, 1991, 10 (01) : 25 - 33

[3] Modeling the late steps in HIV-1 retroviral integrase-catalyzed DNA integration [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (50) : 39287 - 39295

[4] Brown P. O., 1997, P161

[5] HIGH-RESOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF AVIAN-SARCOMA VIRUS INTEGRASE [J]. JOURNAL OF MOLECULAR BIOLOGY, 1995, 253 (02) : 333 - 346

[6] The catalytic domain of avian sarcoma virus integrase: Conformation of the active-site residues in the presence of divalent cations [J]. STRUCTURE, 1996, 4 (01) : 89 - 96

[7] BURKE CJ, 1992, J BIOL CHEM, V267, P9639

[8] RIBBON MODELS OF MACROMOLECULES [J]. JOURNAL OF MOLECULAR GRAPHICS, 1987, 5 (02): : 103 - &

[9] Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: Stimulation by the viral nucleocapsid protein [J]. JOURNAL OF VIROLOGY, 1999, 73 (08) : 6670 - 6679

[10] Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (15) : 8233 - 8238

[1] Molecular mechanisms in retrovirus DNA integration [J]. ANTIVIRAL RESEARCH, 1997, 36 (03) : 139 - 156

[2] STRUCTURAL BASIS FOR THE 3'-5' EXONUCLEASE ACTIVITY OF ESCHERICHIA-COLI DNA-POLYMERASE-I - A 2 METAL-ION MECHANISM [J]. EMBO JOURNAL, 1991, 10 (01) : 25 - 33

[3] Modeling the late steps in HIV-1 retroviral integrase-catalyzed DNA integration [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (50) : 39287 - 39295

[4] Brown P. O., 1997, P161

[5] HIGH-RESOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF AVIAN-SARCOMA VIRUS INTEGRASE [J]. JOURNAL OF MOLECULAR BIOLOGY, 1995, 253 (02) : 333 - 346

[6] The catalytic domain of avian sarcoma virus integrase: Conformation of the active-site residues in the presence of divalent cations [J]. STRUCTURE, 1996, 4 (01) : 89 - 96

[7] BURKE CJ, 1992, J BIOL CHEM, V267, P9639

[8] RIBBON MODELS OF MACROMOLECULES [J]. JOURNAL OF MOLECULAR GRAPHICS, 1987, 5 (02): : 103 - &

[9] Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: Stimulation by the viral nucleocapsid protein [J]. JOURNAL OF VIROLOGY, 1999, 73 (08) : 6670 - 6679

[10] Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (15) : 8233 - 8238