Sensors for detecting biological agents

被引：70

作者：

Sapsford, Kim E. ^{[2
]}

Bradburne, Christopher ^{[1
]}

Delehanty, James B. ^{[1
]}

Medintz, Igor L. ^{[1
]}

机构：

[1] USN, Res Lab, Ctr Bio Mol Sci & Engn Code 6900, Washington, DC 20375 USA

[2] US FDA, Off Sci & Engn Labs, Div Biol, Silver Spring, MD 20903 USA

来源：

MATERIALS TODAY | 2008年 / 11卷 / 03期

关键词：

D O I：

10.1016/S1369-7021(08)70018-X

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Biological agents including viruses, bacteria, and other naturally occurring pathogenic organisms, along with the toxins they produce, are considered far harder to detect and defend against than chemical agents. Here we provide an overview of the predominant molecular sensing technologies for the detection of these agents. This includes biosensing strategies based upon use of antibodies, genomic analysis, biochemical testing, other recognition interactions, and cellular-based responses. We survey some popular sensing approaches, illustrate them with current examples showing how they have been applied, and discuss their intrinsic benefits and potential liabilities. Lastly, within the context of security applications, some approaches for integrating sensing technologies into field-portable devices are discussed.

引用

页码：38 / 49

页数：12

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