Pyridine-Mediated Synthesis of 1,3-Diazetidin-2-ones (Aza-β-lactams): Novel Investigations on Isocyanate-Carbodiimde Reaction

被引：5

作者：

Alizadeh, Abdolali ^{[1
]}

Zohreh, Nasrin ^{[1
]}

Oskueyan, Ghasem ^{[1
]}

Zhu, Long-Guan ^{[2
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

SYNLETT | 2011年 / 17期

关键词：

1,3-diazetidin-2-one; aza-beta-lactam; carbodiimide; arylsulfonyl isocyanate; pyridine; CHROMIUM CARBENE COMPLEXES; ARYL ISOTHIOCYANATES; ONE-POT; CYCLOADDITION; 2-OXO-1,3-DIAZABICYCLO<2.2.0>HEX-5-ENES; CHEMISTRY; DIKETENE; AM1;

D O I：

10.1055/s-0030-1260327

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

The reported cycloaddition reaction of isocyanates and symmetric carbodiimides is reinvestigated in the presence of pyridine. The Huisgen zwitterion generated by the 1:1 addition of pyridine to arylsulfonyl isocyanate is trapped by dialkyl carbodiimide to obtain symmetrical 1,3-diazetidin-2-ones via a novel intramolecular rearrangement.

引用

收藏

页码：2491 / 2494

页数：4

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