YhbO protects cells against multiple stresses

被引：42

作者：

Abdallah, Jad ^{[1
]}

Caldas, Teresa ^{[1
]}

Kthiri, Fatoum ^{[2
]}

Kern, Renee ^{[1
]}

Richarme, Gilbert ^{[1
]}

机构：

[1] Univ Paris 07, Inst Jacques Monod, F-75005 Paris, France

[2] Fac Sci Bizerte, Lab Biochim & Biol Mol, Zarzouna 7021, Bizerte, Tunisia

来源：

JOURNAL OF BACTERIOLOGY | 2007年 / 189卷 / 24期

关键词：

D O I：

10.1128/JB.01208-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

YhbO is a member of the DJ-1/ThiJ/Pfp1 superfamily, which includes chaperones, peptidases, and the Parkinson's disease protein DJ-1. A yhbO-disrupted mutant of Escherichia coli is highly sensitive to oxidative, thermal, UV, and pH stresses, and the putative nucleophilic cysteine C104 of YhbO is required for stress resistance. These results suggest that YhbO affects a central process in stress management.

引用

页码：9140 / 9144

页数：5

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