Vasectomy and prostate cancer in Quebec, Canada

被引：10

作者：

Emard, JF

Drouin, G

Thouez, JP

Ghadirian, P

机构：

[1] Univ Montreal, Ctr Hosp, Hotel Dieu, Unite Rech Epidemiol,Ctr Rech, Montreal, PQ H2W 1T8, Canada

[2] Univ Montreal, Ctr Hosp, Hotel Dieu, Dept Urol, Montreal, PQ H2W 1T8, Canada

[3] Univ Montreal, Dept Geog, Montreal, PQ H3C 3J7, Canada

来源：

HEALTH & PLACE | 2001年 / 7卷 / 02期

关键词：

prostate cancer; vasectomy; birth cohort; association; Quebec male population;

D O I：

10.1016/S1353-8292(01)00005-3

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The present investigation measured the association between vasectomy and prostate cancer (PC) in the male population of Quebec. Canada. The Quebec Health Insurance Board and the Quebec Cancer Registry were our principal sources of information. Lung cancer cases and the male population of Quebec served as controls for comparative purposes. Within a retrospective design. our preliminary results indicate an association between vasectomy and PC. Among the 1925-39 birth cohort of individuals diagnosed with PC in 1990-93, the global odds ratio was 2.6 (95% CI = 1.7-4.3) while it was compared with lung cancer as the control group. This risk increased with the length of time between vasectomy and the diagnosis of cancer. An historical design indicated strong cohesion of the results. Besides, the risk does not vary when we control For the place of residence of the individuals. Vasectomy seems to increase the risk of PC at least 10 years after the operation, but we cannot exclude the impact of a possible detection bias among vasectomized individuals. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：131 / 139

页数：9

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