Self-assembly of double hydrophilic block copolymers in concentrated aqueous solution

被引：51

作者：

Blanazs, Adam ^{[1
]}

Warren, Nicholas J. ^{[1
]}

Lewis, Andrew L. ^{[2
]}

Armes, Steven P. ^{[1
]}

Ryan, Anthony J. ^{[1
]}

机构：

[1] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England

[2] Biocompatibles UK Ltd, Surrey GU9 8QL, England

来源：

SOFT MATTER | 2011年 / 7卷 / 14期

关键词：

DIBLOCK COPOLYMERS; POLYMER-SOLUTIONS; POLY(ETHYLENE GLYCOL); AGGREGATION BEHAVIOR; ORDERED STRUCTURE; MICELLES; VESICLES; DELIVERY; PROTEIN; PHOSPHORYLCHOLINE;

D O I：

10.1039/c1sm05771e

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070305 [高分子化学与物理];

摘要：

We report the unusual aqueous (micro) phase separation of binary mixtures of two biocompatible, hydrophilic homopolymers and the corresponding double-hydrophilic diblock copolymers of poly (ethylene oxide) (PEO) and poly[2-(methacryloyloxy) ethyl phosphorylcholine) (PMPC). SAXS analysis of these double hydrophilic block copolymers in concentrated aqueous solution shows highly hydrated nano-structures and a hydration mechanism is proposed based on these data.

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收藏

页码：6399 / 6403

页数：5

相关论文

共 48 条

[1]

Vesicles and liposomes:: A self-assembly principle beyond lipids [J].

Antonietti, M ;

Förster, S .

ADVANCED MATERIALS, 2003, 15 (16) :1323-1333

[2]

Switching the inside and the outside of aggregates of water-soluble block copolymers with double thermoresponsivity [J].

Arotçaréna, M ;

Heise, B ;

Ishaya, S ;

Laschewsky, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (14) :3787-3793

[3]

Synthesis and solution properties of water-soluble hydrophilic-hydrophobic block copolymers [J].

Baines, FL ;

Billingham, NC ;

Armes, SP .

MACROMOLECULES, 1996, 29 (10) :3416-3420

[4]

BLOCK COPOLYMER THERMODYNAMICS - THEORY AND EXPERIMENT [J].

BATES, FS ;

FREDRICKSON, GH .

ANNUAL REVIEW OF PHYSICAL CHEMISTRY, 1990, 41 (01) :525-557

[5]

Self-Assembled Block Copolymer Aggregates: From Micelles to Vesicles and their Biological Applications [J].

Blanazs, Adam ;

Armes, Steven P. ;

Ryan, Anthony J. .

MACROMOLECULAR RAPID COMMUNICATIONS, 2009, 30 (4-5) :267-277

[6]

Unusual aggregation behavior of a novel tertiary amine methacrylate-based diblock copolymer: Formation of micelles and reverse micelles in aqueous solution [J].

Butun, V ;

Billingham, NC ;

Armes, SP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (45) :11818-11819

[7]

Synthesis and aqueous solution properties of near-monodisperse tertiary amine methacrylate homopolymers and diblock copolymers [J].

Bütün, V ;

Armes, SP ;

Billingham, NC .

POLYMER, 2001, 42 (14) :5993-6008

[8]

DEGENNES PG, 1979, SCALING CONCEPTS POL, P106

[9]

Polymer vesicles [J].

Discher, DE ;

Eisenberg, A .

SCIENCE, 2002, 297 (5583) :967-973

[10]

Phase separation of aqueous mixtures of poly(ethylene oxide) and dextran [J].

Edelman, MW ;

van der Linden, E ;

Tromp, RH .

MACROMOLECULES, 2003, 36 (20) :7783-7790

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