Photo-responsive oligonucleotides carrying azobenzene in the side-chains

被引：53

作者：

Asanuma, H ^{[1
]}

Ito, T ^{[1
]}

Komiyama, M ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Engn, Dept Chem & Biotechnol, Bunkyo Ku, Tokyo 1138656, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 49期

基金：

日本学术振兴会;

关键词：

azo compound; isomerization; phosphoramidite; photochemistry;

D O I：

10.1016/S0040-4039(98)02022-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title oligonucleotides were prepared by using a nw phosphoramidite monomer. The cis-trans isomers with respect to the stereochemistry of the azobenzene residue, obtained on photo-irradiation, were completely resolved by reversed-phase HPLC. The physicochemical properties of these oligonucleotides were significantly changed by the photo-induced isomerization. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：9015 / 9018

页数：4

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