Non-peptide gonadotropin-releasing hormone receptor antagonists

[11] Pharmacological and endocrine characterization of A-198401, an orally active GnRH antagonist, in intact and castrate male rat models [J]. DRUG DEVELOPMENT RESEARCH, 2001, 52 (03) : 485 - 491

[12] Nonpeptide antagonists of neuropeptide receptors: tools for research and therapy [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1997, 18 (10) : 372 - 386

[13] Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (02) : 637 - 647

[14] Determination of the binding mode of thienopyrimidinedione antagonists to the human gonadotropin releasing hormone receptor using structure-activity relationships, site-directed mutagenesis, and homology modeling [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (21) : 6170 - 6176

[15] BOYCE M, 2002, 58 ANN M AM SOC REPR

[16] Pharmacological profile of a new, potent, and long-acting gonadotropin-releasing hormone antagonist: Degarelix [J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 301 (01) : 95 - 102

[17] Unexpected effects of epitope and chimeric tags on gonadotropin-releasing hormone receptors: Implications for understanding the molecular etiology of hypogonadotropic hypogonadism [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (12) : 6107 - 6112

[18] PRIMARY STRUCTURE OF OVINE HYPOTHALAMIC LUTEINIZING HORMONE-RELEASING FACTOR (LRF) [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (01) : 278 - +

[19] Pharmacological profile of MEN91507, a new CysLT1 receptor antagonist [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2002, 451 (03) : 317 - 326

[20] THE DYNAMICS OF GONADOTROPIN INHIBITION IN WOMEN INDUCED BY AN ANTAGONISTIC ANALOG OF GONADOTROPIN-RELEASING HORMONE [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1983, 57 (01) : 62 - 65

[11] Pharmacological and endocrine characterization of A-198401, an orally active GnRH antagonist, in intact and castrate male rat models [J]. DRUG DEVELOPMENT RESEARCH, 2001, 52 (03) : 485 - 491

[12] Nonpeptide antagonists of neuropeptide receptors: tools for research and therapy [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1997, 18 (10) : 372 - 386

[13] Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (02) : 637 - 647

[14] Determination of the binding mode of thienopyrimidinedione antagonists to the human gonadotropin releasing hormone receptor using structure-activity relationships, site-directed mutagenesis, and homology modeling [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (21) : 6170 - 6176

[15] BOYCE M, 2002, 58 ANN M AM SOC REPR

[16] Pharmacological profile of a new, potent, and long-acting gonadotropin-releasing hormone antagonist: Degarelix [J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 301 (01) : 95 - 102

[17] Unexpected effects of epitope and chimeric tags on gonadotropin-releasing hormone receptors: Implications for understanding the molecular etiology of hypogonadotropic hypogonadism [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (12) : 6107 - 6112

[18] PRIMARY STRUCTURE OF OVINE HYPOTHALAMIC LUTEINIZING HORMONE-RELEASING FACTOR (LRF) [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (01) : 278 - +

[19] Pharmacological profile of MEN91507, a new CysLT1 receptor antagonist [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2002, 451 (03) : 317 - 326

[20] THE DYNAMICS OF GONADOTROPIN INHIBITION IN WOMEN INDUCED BY AN ANTAGONISTIC ANALOG OF GONADOTROPIN-RELEASING HORMONE [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1983, 57 (01) : 62 - 65