Comparing areas under receiver operating characteristic curves: Potential impact of the "last" experimentally measured operating point
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作者:
Gur, David
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Univ Pittsburgh, Dept Radiol, Grad Sch Publ Hlth, Pittsburgh, PA 15213 USAUniv Pittsburgh, Dept Radiol, Grad Sch Publ Hlth, Pittsburgh, PA 15213 USA
Gur, David
[1
]
Bandos, Andriy I.
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Univ Pittsburgh, Dept Biostat, Grad Sch Publ Hlth, Pittsburgh, PA 15213 USAUniv Pittsburgh, Dept Radiol, Grad Sch Publ Hlth, Pittsburgh, PA 15213 USA
Bandos, Andriy I.
[2
]
Rockette, Howard E.
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Univ Pittsburgh, Dept Biostat, Grad Sch Publ Hlth, Pittsburgh, PA 15213 USAUniv Pittsburgh, Dept Radiol, Grad Sch Publ Hlth, Pittsburgh, PA 15213 USA
Rockette, Howard E.
[2
]
机构:
[1] Univ Pittsburgh, Dept Radiol, Grad Sch Publ Hlth, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Dept Biostat, Grad Sch Publ Hlth, Pittsburgh, PA 15213 USA
A specific issue related to the selection of the analytic tool used when comparing the estimated performance of systems within the receiver operating characteristic (ROC) paradigm is reviewed. This issue is related to the possible effect of the last experimentally ascertained ROC data point in terms of highest true-positive and false-positive fractions. An example of a case is presented where the selection of a specific analysis approach could affect the study conclusion from being not statistically significant for parametric analysis and significant for nonparametric analysis. This is followed by recommendations that should help prevent misinterpretation of results. (c) RSNA, 2008.