Prevalence effect in a laboratory environment

被引:92
作者
Gur, D [1 ]
Rockette, HE [1 ]
Armfield, DR [1 ]
Blachar, A [1 ]
Bogan, JK [1 ]
Brancatelli, G [1 ]
Britton, CA [1 ]
Brown, ML [1 ]
Davis, PL [1 ]
Ferris, JV [1 ]
Fuhrman, CR [1 ]
Golla, SK [1 ]
Katyal, S [1 ]
Lacomis, JM [1 ]
McCook, BM [1 ]
Thaete, FL [1 ]
Warfel, TE [1 ]
机构
[1] Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15213 USA
关键词
diagnostic radiology; observer performance; receiver operating characteristic (ROC) curve; statistical analysis;
D O I
10.1148/radiol.2281020709
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To measure observer performance at various levels of prevalence. MATERIALS AND METHODS: A multiobserver multiabnormality receiver operating characteristic (ROC) study to assess the effect of prevalence on observer performance was conducted. Fourteen observers, including eight faculty members, two fellows, and four residents, interpreted 1,632 posteroanterior chest images with five prevalence levels by using a nested study design. Performance comparisons were accomplished by using a multireader multicase approach to assess the effect of prevalence from 28% (69 of 249) to 2% (31 of 1,577) on diagnostic accuracy. The mean times required to review and report a case were analyzed and compared for different levels of prevalence and readers' experience. RESULTS: Area under the ROC curve demonstrated that, with the study experimental conditions, no significant effect could be measured as a function of prevalence (P >.05) for any abnormality, group of cases, or readers. There were no significant differences (P >.05) in the mean times required to review and report cases at different prevalence levels and with different groups of readers. CONCLUSION: The consistency in the results and the size of this study suggest that with laboratory conditions, if a prevalence effect exists, it is quite small in magnitude; hence, it will not likely alter conclusions derived from such studies. (C) RSNA, 2003.
引用
收藏
页码:10 / 14
页数:5
相关论文
共 22 条
[1]   EFFICIENT UTILIZATION OF NON-NUMERICAL INFORMATION IN QUANTITATIVE-ANALYSIS - GENERAL-THEORY AND CASE OF SIMPLE ORDER [J].
ABELSON, RP ;
TUKEY, JW .
ANNALS OF MATHEMATICAL STATISTICS, 1963, 34 (04) :1347-&
[2]  
BROGDON BG, 1983, RADIOL CLIN N AM, V21, P633
[3]   RECEIVER OPERATING CHARACTERISTIC RATING ANALYSIS - GENERALIZATION TO THE POPULATION OF READERS AND PATIENTS WITH THE JACKKNIFE METHOD [J].
DORFMAN, DD ;
BERBAUM, KS ;
METZ, CE .
INVESTIGATIVE RADIOLOGY, 1992, 27 (09) :723-731
[4]   Context bias - A problem in diagnostic radiology [J].
Egglin, TKP ;
Feinstein, AR .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 276 (21) :1752-1755
[5]   Effects of prevalence on visual search and decision making in fracture detection [J].
Ethell, SC ;
Manning, D .
MEDICAL IMAGING 2001: IMAGE PERCEPTION AND PERFORMANCE, 2001, 4324 :249-257
[6]   THE EFFECT OF VARYING SPATIAL-RESOLUTION ON THE DETECTABILITY OF DIFFUSE PULMONARY NODULES - ASSESSMENT WITH DIGITIZED CONVENTIONAL RADIOGRAPHS [J].
FOLEY, WD ;
WILSON, CR ;
KEYES, GS ;
DIBIANCA, FA ;
SCANLON, GT ;
SCHLEUTER, D ;
LAWSON, TL .
RADIOLOGY, 1981, 141 (01) :25-31
[7]  
Green DM., 1966, Signal detection theory and psychophysics, P1969
[8]   Effects of luminance and resolution on observer performance with chest radiographs [J].
Herron, JM ;
Bender, TM ;
Campbell, WL ;
Sumkin, JH ;
Rockette, HE ;
Gur, D .
RADIOLOGY, 2000, 215 (01) :169-174
[9]   DISEASE PREVALENCE AND RADIOLOGICAL DECISION-MAKING [J].
KUNDEL, HL .
INVESTIGATIVE RADIOLOGY, 1982, 17 (01) :107-109
[10]   Disease prevalence and the index of detectability: A survey of studies of lung cancer detection by chest radiography [J].
Kundel, HL .
MEDICAL IMAGING 2000: IMAGE PERCEPTION AND PERFORMANCE, 2000, 3981 :135-144