Lack of β-methylamino-L-alanine in brain from controls, AD, or Chamorros with PDC

被引：93

作者：

Montine, TJ ^{[1
]}

Li, K ^{[1
]}

Perl, DP ^{[1
]}

Galasko, D ^{[1
]}

机构：

[1] Univ Washington, Dept Pathol, Seattle, WA 98104 USA

来源：

NEUROLOGY | 2005年 / 65卷 / 05期

关键词：

D O I：

10.1212/01.wnl.0000174523.62022.52

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

High levels of beta-methylamino-L-alanine (BMAA), a putative neurotoxin, have been reported in brain samples from Chamorros and patients with Alzheimer disease (AD) from western Canada. The authors assayed free BMAA in the brains of five control subjects and five patients with AD from the US Pacific Northwest as well as Chamorros with and without Parkinson-dementia complex. In contrast to others, they detected no free BMAA in any of these samples.

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页码：768 / 769

页数：2

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