Mycoplasma pneumoniae and central nervous system complications:: A review.

被引：76

作者：

Guleria, R ^{[1
]}

Nisar, N ^{[1
]}

Chawla, TC ^{[1
]}

Biswas, NR ^{[1
]}

机构：

[1] All India Inst Med Sci, Dept Med, New Delhi 110029, India

来源：

JOURNAL OF LABORATORY AND CLINICAL MEDICINE | 2005年 / 146卷 / 02期

关键词：

D O I：

10.1016/j.lab.2005.04.006

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Mycoplasma pneumoniae is a common cause of community-acquired pneumonia. Little is known about the extrapulmonary manifestations of this organism. Numerous central nervous system (CNS) manifestations have been described with M. pneumoniae. CNS involvement is probably the most common site of involvement in addition to the respiratory system. Up to 7% of patients hospitalized with M. pneumoniae may have CNS symptoms. Common CNS presentations include encephalitis, aseptic meningitis, polyradiculitis, cerebellar ataxia, and myelitis. The mechanism behind these CNS manifestations remains unclear. Direct invasion, neurotoxin production, or an immune-mediated mechanism has been proposed. Newer diagnostic techniques for the direct detection of the antigen and the microorganism are proving useful for the detection of extrapulmonary disease. This review comprehensively reviews the CNS complications that have been reported with M. pneumoniae.

引用

页码：55 / 63

页数：9

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