New and future therapies for lupus nephritis

被引：7

作者：

Appel, Gerald B. ^{[1
,2
]}

机构：

[1] Columbia Univ, Med Ctr, New York Presbyterian Hosp, New York, NY USA

[2] Columbia Univ, Coll Phys & Surg, New York, NY USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2012年 / 79卷 / 02期

关键词：

MYCOPHENOLATE-MOFETIL; LONG-TERM; INTRAVENOUS CYCLOPHOSPHAMIDE; RITUXIMAB; EFFICACY; ERYTHEMATOSUS; INDUCTION; SAFETY; TRIAL;

D O I：

10.3949/ccjm.78gr.11004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Based on data from randomized controlled trials over the past decade, oral mycophenolate (CellCept) now rivals intravenous cyclophosphamide (Cytoxan) as a first-line therapy for lupus nephritis, offering similar efficacy but less toxicity. The roles of rituximab (Rituxan) and new immunomodulatory agents are being explored. Creativity in treating lupus nephritis is needed; one regimen does not fit all.

引用

页码：134 / 140

页数：7

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