RACE:: Remote Analysis Computation for gene Expression data

被引:52
作者
Psarros, M
Heber, S
Sick, M
Thoppae, G
Harshman, K
Sick, B [1 ]
机构
[1] Univ Lausanne, Ctr Integrat Genom, DNA Array Facil, Lausanne, Switzerland
[2] N Carolina State Univ, Bioinformat Res Ctr, Raleigh, NC 27695 USA
关键词
D O I
10.1093/nar/gki490
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Remote Analysis Computation for gene Expression data ( RACE) suite is a collection of bioinformatics web tools designed for the analysis of DNA microarray data. RACE performs probe-level data preprocessing, extensive quality checks, data visualization and data normalization for Affymetrix Gene Chips. In addition, it offers differential expression analysis on normalized expression levels from any array platform. RACE estimates the false discovery rates of lists of potentially regulated genes and provides a Gene Ontology-term analysis tool for GeneChip data to support the biological interpretation and annotation of results. The analysis is fully automated but can be customized by flexible parameter settings. To offer a convenient starting point for subsequent analyses, and to provide maximum transparency, the R scripts used to generate the results can be downloaded along with the output files. RACE is freely available for use at http://race.unil.ch.
引用
收藏
页码:W638 / W643
页数:6
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