Phenolic composition and biological activities of Tunisian Nigella sativa L. shoots and roots

被引：189

作者：

Bourgou, Soumaya ^{[1
]}

Ksouri, Riadh ^{[2
]}

Bellila, Amor ^{[1
]}

Skandrani, Ines ^{[3
]}

Falleh, Hanen ^{[2
]}

Marzouk, Brahim ^{[1
]}

机构：

[1] Biotechnol Ctr Borj Cedria Technopol, Aromat & Med Plants Unit, Hammam Lif 901, Tunisia

[2] Biotechnol Ctr Borj Cedria Technopol, Lab Plant Adaptat Abiot Stress, Hammam Lif 901, Tunisia

[3] Fac Pharm, Dept Biochem & Mol Biol, Monastir 5000, Tunisia

来源：

COMPTES RENDUS BIOLOGIES | 2008年 / 331卷 / 01期

关键词：

Nigella sativa L; shoots; roots; antiradical activity; reducing power; chelating power; antimutagenic activity; phenolic composition;

D O I：

10.1016/j.crvi.2007.11.001

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In the present investigation, methanolic extracts from shoots and roots of Tunisian Nigella sativa were assayed for their antioxidant and antimutagenic activities. The phenolic composition of the methanolic extracts was determined by RP-HPLC. The predominant phenolic compound was vanillic acid with a mean concentration of 143.21 and 89.94 mg per 100 g dry weight of shoots and roots, respectively. Shoots and roots showed comparable and strong superoxide scavenger activity; however, shoots exhibited higher DPPH radical scavenging, reducing and chelating activities than roots. Mutagenic and antimutagenic activities were determined by using the Ames test. Shoots and roots demonstrated important antimutagenic effects. Roots exhibited stronger activity than shoots with an inhibition percentage of 71.32%.

引用

页码：48 / 55

页数：8

共 41 条

[31] Oxidative stability of black cumin (Nigella sativa L.), coriander (Coriandrum sativum L.) and niger (Guizotia abyssinica Cass.) crude seed oils upon stripping [J].

Ramadan, MF ;

Mörsel, JT .

EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 2004, 106 (01) :35-43

[32] Structure-antioxidant activity relationships of flavonoids and phenolic acids [J].

RiceEvans, CA ;

Miller, NJ ;

Paganga, G .

FREE RADICAL BIOLOGY AND MEDICINE, 1996, 20 (07) :933-956

[33] Alkylperoxyl radical-scavenging activity of various flavonoids and other phenolic compounds: Implications for the anti-tumor-promoter effect of vegetables [J].

Sawa, T ;

Nakao, M ;

Akaike, T ;

Ono, K ;

Maeda, H .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1999, 47 (02) :397-402

[34]

Scalbert A, 2005, AM J CLIN NUTR, V81, p215S, DOI 10.1093/ajcn/81.1.215S

[35] ANTIOXIDATIVE PROPERTIES OF XANTHAN ON THE AUTOXIDATION OF SOYBEAN OIL IN CYCLODEXTRIN EMULSION [J].

SHIMADA, K ;

FUJIKAWA, K ;

YAHARA, K ;

NAKAMURA, T .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1992, 40 (06) :945-948

[36] Antioxidant potency of cumin varieties - cumin, black cumin and bitter cumin - on antioxidant systems [J].

Thippeswamy, N ;

Naidu, KA .

EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2005, 220 (5-6) :472-476

[37] Investigations on the antioxidant activity of fruit and vegetable aqueous extracts on superoxide radical anion using chemiluminescence techniques [J].

Triantis, T ;

Stelakis, A ;

Dimotikali, D ;

Papadopoulos, K .

ANALYTICA CHIMICA ACTA, 2005, 536 (1-2) :101-105

[38] Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products [J].

Velioglu, YS ;

Mazza, G ;

Gao, L ;

Oomah, BD .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1998, 46 (10) :4113-4117

[39] PLANT FLAVONOIDS, ESPECIALLY TEA FLAVONOLS, ARE POWERFUL ANTIOXIDANTS USING AN IN-VITRO OXIDATION MODEL FOR HEART-DISEASE [J].

VINSON, JA ;

DABBAGH, YA ;

SERRY, MM ;

JANG, JH .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1995, 43 (11) :2800-2802

[40] Effects of extraction solvent mixtures on antioxidant activity evaluation and their extraction capacity and selectivity for free phenolic compounds in barley (Hordeum vulgare L.) [J].

Zhao, Haifeng ;

Dong, Jianjun ;

Lu, Jian ;

Chen, Jian ;

Li, Yin ;

Shan, Lianju ;

Lin, Yan ;

Fan, Wei ;

Gu, Guoxian .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (19) :7277-7286

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