Anxiety and cardiovascular reactivity: the basal forebrain cholinergic link

被引:169
作者
Berntson, GG
Sarter, M
Cacioppo, JT
机构
[1] Ohio State Univ, Dept Psychol, Columbus, OH 43210 USA
[2] Ohio State Univ, Program Neurosci, Columbus, OH 43210 USA
关键词
acetylcholine; emotion; anxiety; benzodiazepine receptor; cardiovascular system; cognition; fear; FG; 7142; GABA; heart; basal forebrain; cortex;
D O I
10.1016/S0166-4328(98)00041-2
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The relations between anxiety states and autonomic functions are considered from the vantage of a model of the neural systems underlying anxiety and autonomic control. An important component of this model is the involvement of the basal forebrain cortical cholinergic system that is seen to play a crucial role in the cognitive aspects of anxiety, and the links between anxiety and autonomic regulation. An additional aspect of the model is the detailing of the routes by which autonomic reactivity and associated visceral afference can modulate more rostral components of the system, The proposed model offers a more comprehensive framework for research on the neurobiology of anxiety and autonomic control. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:225 / 248
页数:24
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