Volumetric diffuse optical tomography of brain activity

被引：137

作者：

Culver, JP ^{[1
]}

Siegel, AM ^{[1
]}

Stott, JJ ^{[1
]}

Boas, DA ^{[1
]}

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Martinos Ctr Biomed Imaging, Charlestown, MA 02129 USA

来源：

OPTICS LETTERS | 2003年 / 28卷 / 21期

关键词：

D O I：

10.1364/OL.28.002061

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present three-dimensional diffuse optical tomography of the hemodynamic response to somatosensory stimulation in a rat. These images show the feasibility of volumetrically imaging the functional response to brain activity with diffuse light. A combination of positional optode calibration and contrast-to-noise ratio weighting was found to improve imaging performance. (C) 2003 Optical Society of America.

引用

收藏

页码：2061 / 2063

页数：3

相关论文

共 14 条

[1] Three-dimensional optical tomography of hemodynamics in the human head [J].

Bluestone, AY ;

Abdoulaev, G ;

Schmitz, CH ;

Barbour, RL ;

Hielscher, AH .

OPTICS EXPRESS, 2001, 9 (06) :272-286

[2] Simultaneous imaging and optode calibration with diffuse optical tomography [J].

Boas, DA ;

Gaudette, T ;

Arridge, SR .

OPTICS EXPRESS, 2001, 8 (05) :263-270

[3] In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies [J].

Cheung, C ;

Culver, JP ;

Takahashi, K ;

Greenberg, JH ;

Yodh, AG .

PHYSICS IN MEDICINE AND BIOLOGY, 2001, 46 (08) :2053-2065

[4] Simultaneous near-infrared spectroscopy monitoring of left and right occipital areas reveals contra-lateral hemodynamic changes upon hemi-field paradigm [J].

Colier, WNJM ;

Quaresima, V ;

Wenzel, R ;

van der Sluijs, MC ;

Oeseburg, B ;

Ferrari, M ;

Villringer, A .

VISION RESEARCH, 2001, 41 (01) :97-102

[5] Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia [J].

Culver, JP ;

Durduran, T ;

Furuya, T ;

Cheung, C ;

Greenberg, JH ;

Yodh, AG .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2003, 23 (08) :911-924

[6] Optimization of optode arrangements for diffuse optical tomography: A singular-value analysis [J].

Culver, JP ;

Ntziachristos, V ;

Holboke, MJ ;

Yodh, AG .

OPTICS LETTERS, 2001, 26 (10) :701-703

[7] On-line optical imaging of the human brain with 160-ms temporal resolution [J].

Franceschini, MA ;

Toronov, V ;

Filiaci, ME ;

Gratton, E ;

Fantini, S .

OPTICS EXPRESS, 2000, 6 (03) :49-57

[8]

Mandeville JB, 1999, MAGNET RESON MED, V42, P591, DOI 10.1002/(SICI)1522-2594(199909)42:3<591::AID-MRM23>3.0.CO

[9]

2-8

[10] EXPERIMENTAL IMAGES OF HETEROGENEOUS TURBID MEDIA BY FREQUENCY-DOMAIN DIFFUSING-PHOTON TOMOGRAPHY [J].

OLEARY, MA ;

BOAS, DA ;

CHANCE, B ;

YODH, AG .

OPTICS LETTERS, 1995, 20 (05) :426-428