Intracellular hydrogelation of small molecules inhibits bacterial growth

被引：212

作者：

Yang, Zhimou

Liang, Gaolin

Guo, Zufeng

Guo, Zhihong

Xu, Bing

机构：

[1] Hong Kong Univ Sci & Technol, Hong Kong, Peoples R China

[2] Hong Kong Univ Sci & Technol, Canc Res Ctr, Hong Kong, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 43期

关键词：

D O I：

10.1002/anie.200701697

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Control from within: Supramolecular hydrogelation to form nanostructures intracellularly (see picture) has been developed as a new methodology to control the fate of cells. Enzyme-regulated self-assembly of small molecules inside cells could lead to a new paradigm for managing cellular processes, understanding cellular functions, and developing new therapeutics through supramolecular chemistry. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：8216 / 8219

页数：4

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