Termination of translation: interplay of mRNA, rRNAs and release factors?

被引：185

作者：

Kisselev, L ^{[1
]}

Ehrenberg, M

Frolova, L

机构：

[1] VA Engelhardt Mol Biol Inst, Moscow 119991, Russia

[2] Uppsala Univ, Dept Cell & Mol Biol, BMC, S-75124 Uppsala, Sweden

来源：

EMBO JOURNAL | 2003年 / 22卷 / 02期

关键词：

polypeptide release factors; ribosomes; RNA-protein recognition; translation;

D O I：

10.1093/emboj/cdg017

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Termination of translation in eukaryotes has focused recently on functional anatomy of polypeptide chain release factor, eRF1, by using a variety of different approaches. The tight correlation between the domain structure and different functions of eRF1 has been revealed. Independently, the role of prokaryotic RF1/2 in GTPase activity of RF3 has been deciphered, as well as RF3 function itself.

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收藏

页码：175 / 182

页数：8

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