Au(I)-catalyzed cyclization of enynes bearing an olefinic cycle

被引：71

作者：

Lee, Sang Ick

Kim, Soo Min

Choi, Mi Ra

Kim, Sun Young

Chung, Young Keun ^{[1
]}

Han, Won-Sik

Kang, Sang Ook

机构：

[1] Seoul Natl Univ, Coll Nat Sci, Dept Chem, Intelligent Text Syst Res Ctr, Seoul 151747, South Korea

[2] Korea Univ, Dept Chem, Chociwon 339700, Chung Nam, South Korea

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 25期

关键词：

D O I：

10.1021/jo061254r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Gold(I)-catalyzed cyclization of enynes containing an olefinic cycle has been studied. The introduction of an olefinic ring instead of a terminal alkene in enynes dramatically increased the yield of the reaction. Enynes having an olefinic cycle were prepared by a rhodium-catalyzed intermolecular [4 + 2] cycloaddition of diynes with butadiene. Consecutive rhodium-catalyzed Diels-Alder/gold(I)-catalyzed cycloisomerization reactions were integrated in a one-pot reaction.

引用

页码：9366 / 9372

页数：7

共 34 条

[1] Two birds with one metallic stone: Single-pot catalysis of fundamentally different transformations [J].