Homocysteine, oxidative stress, and vascular disease

被引：90

作者：

Welch, GN

Upchurch, GR

Loscalzo, J

机构：

[1] Boston University, Brigham and Women's Hospital, Boston

[2] Evans Department of Medicine, Whitaker Cardiovascular Institute, Boston University School of Medicine

[3] Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston

来源：

HOSPITAL PRACTICE | 1997年 / 32卷 / 06期

关键词：

D O I：

10.1080/21548331.1997.11443510

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

First recognized in patients with rare inborn errors of metabolism, the association of elevated plasma homocysteine concentrations with atherosclerosis and thrombosis now seems relevant to the general population as well, The mechanism of injury appears to involve oxidative damage to endothelial cells, Vitamin supplementation can normalize homocysteine levels and may lower the incidence of atherothrombotic vascular disease.

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页码：81 / &

页数：8

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