Bidentate carbenoid ester coordination in ruthenium(II) Schiff-base complexes leading to excellent levels of diastereo- and enantioselectivity in catalytic alkene cyclopropanation

被引：67

作者：

Munslow, IJ ^{[1
]}

Gillespie, KM ^{[1
]}

Deeth, RJ ^{[1
]}

Scott, P ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 17期

关键词：

D O I：

10.1039/b104964j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Exceptionally high stereoselectivity (ee less than or equal to 98%, dr less than or equal to 99:1) in the cyclopropanation of alkenes with ethyl diazoacetate using a non-planar ruthenium(II) Schiff-base precatalyst is a result of eta C-2,O binding of the carbenoid ester intermediate, according to DFT calculations.

引用

页码：1638 / 1639

页数：2

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