AN EFFICIENT SYNTHESIS OF THIOESTERS VIA TFA-CATALYZED REACTION OF CARBOXYLIC ACID AND THIOLS: REMARKABLY FACILE C-S BOND FORMATION

被引：24

作者：

El-Azab, Adel S. ^{[1
,2
]}

Abdel-Aziz, Alaa A. -M. ^{[1
,3
]}

机构：

[1] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia

[2] Al Azhar Univ, Fac Pharm, Dept Organ Chem, Nasr City, Cairo, Egypt

[3] Univ Mansoura, Fac Pharm, Dept Med Chem, Mansoura, Egypt

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2012年 / 187卷 / 09期

关键词：

Synthesis; trifluroacetic acid; carboxylic acid; thioester; ester; x-ray crystallography; CONJUGATE ADDITION; ALKYL-HALIDES; PEPTIDE; CONVENIENT; ESTERS; DERIVATIVES; DISULFIDES; AZIRIDINES; LIGATION; ROUTE;

D O I：

10.1080/10426507.2012.664220

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A general, facile, and efficient new synthetic path to thioesters was established by employing defined TFA-catalyzed reaction of carboxylic acid and thiol under mild conditions. The structure of the newly synthesized compounds was determined by infrared spectroscopy, nuclear magnetic resonance, and a single crystal X-ray crystallographic analysis. Supplemental materials are available for this paper. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

引用

页码：1046 / 1055

页数：10

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