Assisted conception in HIV discordant couples: evaluation of semen processing techniques in reducing HIV viral load

被引：28

作者：

Chrystie, IL ^{[1
]}

Mullen, JE

Braude, PR

Rowell, P

Williams, E

Elkington, N

de Ruiter, A

Rice, K

Kennedy, J

机构：

[1] Guys & St Thomas Hosp Trust, Dept Virol, London SE1 7EH, England

[2] Guys & St Thomas Hosp Trust, Assisted Concept Unit, London SE1 7EH, England

[3] Guys & St Thomas Hosp Trust, Dept Genitourinary Med, London SE1 7EH, England

[4] Guys & St Thomas Hosp Trust, Haemophilia Ctr, London SE1 7EH, England

[5] Guys & St Thomas Hosp Trust, Antenatal Clin, London SE1 7EH, England

来源：

JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 1998年 / 41卷 / 1-2期

关键词：

HIV; assisted conception; semen; spermatozoa; discordant couples;

D O I：

10.1016/S0165-0378(98)00066-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Artificial insemination with motile spermatozoa prepared from HIV-infected men using standard procedures has been employed with many HIV-discordant couples. We have demonstrated that processing semen from HIV positive men can reduce HIV levels, measured as HIV1 RNA copies/ml using nucleic acid based sequence amplification (NASBA), to undetectable levels (less than 400 copies/ml) but not in all samples. We believe that all processed samples should be tested prior to insemination. (C) 1998 Published by Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：301 / 306

页数：6

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