CNS effects of heavy particle irradiation in space: Behavioral implications

被引：42

作者：

Joseph, JA ^{[1
]}

Erat, S

Rabin, BM

机构：

[1] Tufts Univ, USDA, Human Nutr Res Ctr Aging, Boston, MA 02111 USA

[2] Univ Maryland, Baltimore, MD 21228 USA

来源：

LIFE SCIENCES: SPACE FLIGHT AND THE CENTRAL NERVOUS SYSTEM: THE POTENTIAL INDEPENDENT AND SYNERGISTIC EFFECTS OF MICROGRAVITY AND RADIATION | 1998年 / 22卷 / 02期

关键词：

D O I：

10.1016/S0273-1177(98)80012-4

中图分类号：

V [航空、航天];

学科分类号：

08 ; 0825 ;

摘要：

Research from several sources indicates that young (3 mo) rats exposed to heavy particle irradiation (Fe-56 irradiation) produces changes in motor behavior as well as alterations in neuronal transmission similar to those seen in aged (22-24 mo) rats. These changes are specific to neuronal systems that are affected by aging. Since Fe-56 particles make up approximately 1-2% of cosmic rays, these findings suggest that the neuronal effects of heavy particle irradiation on long-term space flights may be significant, and may even supercede subsequent mutagenic effects in their mission capabilities. It is suggested that among other methods, it may be possible to utilize nutritional modification procedures to offset the putative delterious effects of these particles in space. Published by Elsevier Science Ltd on behalf of COSPAR.

引用

页码：209 / 216

页数：8

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