The new biomarkers of prostate cancer

被引：4

作者：

Bessede, Th ^{[1
]}

机构：

[1] Hop Bicetre, Serv Urol, F-94275 Le Kremlin Bicetre, France

来源：

PROGRES EN UROLOGIE | 2011年 / 21卷

关键词：

Risk marker; Prostate Health Index; PCA3; Gene fusion; DENSITY; URINE; RISK; GENE; PCA3;

D O I：

10.1016/S1166-7087(11)70014-8

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

100201 [内科学]; 100221 [泌尿外科学];

摘要：

Biomarkers of prostate cancer can assess a presence risk or an evolution risk of the disease. The integration of temporal and clinical data during the interpretation of a PSA dosage improves its performance. Trough a performing algorithm, the Phi index (Prostate Health Index) combines the results of total PSA, free PSA, and pro-PSA. The ration of urinary PCA3 and urinary PSA determines a powerful marker to be used in difficult diagnostic situations. Gene fusions in prostate cancer are promising biomarkers and eventual therapeutic targets. The cost of these new biomarkers is limiting their current use to individual situations. (C) 2011 Elsevier Masson SAS. All rights reserved.

引用

页码：S63 / S67

页数：5

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